EFEK ANTI-INFLAMASI EMULGEL MINYAK BIJI PALA (Myristica fragrans) PADA MENCIT ANTI-INFLAMMATORY EFFECT OF NUTMEG OIL (Myristica fragrans) EMULGEL IN MICE MODEL
Main Article Content
Abstract
Studi inflamasi pada kulit dengan pemberian minyak biji pala (Myristica fragrans) menjadi salah satu inovasi yang terus dikembangkan hingga saat ini. Penelitian sebelumnya menunjukkan bahwa formulasi elmulgel minyak biji pala memiliki potensi inhibitor peradangan berdasarkan komponen senyawa dan stabil secara fisik. Tujuan penelitian untuk mengetahui efek antiinflamasi elmulgel minyak biji pala pada model hewan uji mencit dengan induksi karagen 3%. Emulgel uji sediaan EMBP 3% (Emulgel minyak biji pala 3%), EMBP (Emulgel minyak biji pala 4,5%), EMBP (Emulgel minyak biji pala 6%). Metode yang digunakan inflammation associated edema untuk mengukur tebal lipatan kulit punggung hewan uji. Untuk mendapatkan perubahan lipatan punggung yang diinduksi dengan agen berdasarkan interval waktu. Hasil menunjukkan bahwa pemberian secara topical emulgel minyak biji pala memiliki aktivitas sebagai anti inflamasi. Formula berpotensi sebagai antiinflamasi tertinggi yaitu EMBP 3%.
Kata kunci : Biji Pala, Anti-inflamasi, Minyak atsiri, Emulgel.
Article Details
Copyright Notice
 The author whose manuscript was published agreed to the following provisions:
- The publication right of all journal material published / released on the E-Journal website of the Medical Science Journal: The Pharmaceutical Scientific Journal is held by the editorial board with the author's knowledge (the moral rights remain the manuscript's author).
- Formal legal provisions for access to digital articles in electronic journals are subject to Creative Commons Attribution-ShareAlike (CC BY-SA) license terms, which means Medical Science Journal: Pharmaceutical Scientific Journal has the right to store, transfer media / format, manage in the form of database (database), maintain, and publish articles without asking permission from the author as long as they include the author's name as the copyright owner.
- Manuscripts that are published / released in print and electronically are open access for educational, research and library purposes. In addition to these objectives, the editorial board is not responsible for violations of copyright law.
Â
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.