UJI DAYA HAMBAT EKSTRAK KENTAL DAUN KRATOM (Mitragyna speciosa Korth) TERHADAP BAKTERI Propionibacterium acnes SEBAGAI PENYEBAB JERAWAT
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Abstract
Telah dilakukan penelitian dengan judul “ Uji Daya Hambat Ekstrak Kental Daun Kratom (Mitragyna speciosa Korth) terhadap Pertumbuhan Bakteri Propionibacterium acnes Sebagai Penyebab Jerawat. Penelitian ini bertujuan untuk mengetahui ada tidaknya daya hambat dan konsentrasi berapa ekstrak kental daun kratom dapat menghambat pertumbuhan bakteri Propionibacterium acnes. Pengujian daya hambat dilakukan dengan metode difusi cakram disc dengan konsentrasi yang berbeda yaitu konsentrasi 5%, 10%, 15%, 20%, 25%, kontrol positif dan kontrol negatif. Hasil pengukuran rata-rata diameter daya hambat yaitu konsentrasi 5% sebesar 8,6 mm, 10% sebesar 12,2 mm, 15% sebesar 12,6 mm, 20% sebesar 13,3 mm, 25% sebesar 14,7 mm, kontrol positif sebesar 21,92 mm dan kontrol negatif tidak menghasilkan diameter daya hambat. Hasil penelitian menunjukkan bahwa ekstrak kental daun kratom mempunyai daya hambat terhadap pertumbuhan bakteri Escherichia coli dan ekstrak daun kratom sudah mampu menghambat pertumbuhan bakteri Propionibacterium acnes pada konsentrasi 5% dengan diameter daya hambat sebesar 8,6 mm.
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Pharmacology
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